Clean Sweep Live Auction on Wed. May 1st. Click to view the full inventory

DOTmed Home MRI Oncology Ultrasound Molecular Imaging X-Ray Cardiology Health IT Business Affairs
News Home Parts & Service Operating Room CT Women's Health Proton Therapy Endoscopy HTMs Pediatrics
Aktueller Standort:
> This Story

Log in oder Register to rate this News Story
Forward Printable StoryPrint Comment




Molecular Imaging Homepage

Louisiana getting $14 million Center for Molecular Imaging and Therapy Increasing research opportunities, collaboration and radiopharmaceuticals

DOE transfers land to Coquí Pharma for isotope production facility Will be used primarily to produce Mo-99

Amyloid PET scans help with Alzheimer's clinical management New insights from the 11,000 patient IDEAS study

United Imaging's total-body PET scanner shows promise in four new studies Faster scans, lower dose and 'a level of detail never seen in PET'

NorthStar buys IBA electron accelerators for Mo-99 production Will increase production capacity and efficiencies

RadioMedix and Vect-Horus to develop brain theranostic agent for brain cancer Provide diagnosis and treatment of Glioblastoma Multiforme (GBM)

NIH awards $1.8 million to Magnetic Insight for neurovascular MPI Detects magnetic nanoparticle tracers, enables deep-tissue imaging

DOE to cut Moly-99 deals with four US firms Could be as much as $15 million per company, with partners matching awarded amounts

Women's brains appear three years younger than men's at the same age: PET study A machine-learning algorithm assisted with the analysis

Dennis Durmis MITA names chair of board of directors

An experimental form of PET
imaging has uncovered elevated
amounts of abnormal tau protein in
live subjects with symptoms
of CTE

PET uncovers abnormal tau deposits associated with CTE in live subjects

by John R. Fischer , Staff Reporter
An experimental form of PET imaging may potentially enable the diagnosis of chronic traumatic encephalopathy in live subjects at some point in the future, according to a new study.

Researchers from Boston and Arizona performed flortaucipir PET scans on a number of living former National Football League players, finding elevated amounts of abnormal tau protein in their brains, in regions affected by CTE.

Story Continues Below Advertisement

Servicing GE Nuclear Medicine equipment with OEM trained engineers

We offer full service contracts, PM contracts, rapid response, time and material,camera relocation. Nuclear medicine equipment service provider since 1975. Click or call now for more information 800 96 NUMED

"Currently if is not possible to assess abnormal tau accumulation in the brain during life. We must perform an autopsy of the brain and look for the abnormal tau," Charles H. Adler, professor of neurology at Mayo Clinic College of Medicine at the Mayo Clinic Arizona, told HCB News. "That is why developing the PET scan is so critical to the field."

A neurodegenerative disease, CTE is associated with a history of repetitive head impacts, including those that may or may not be associated with concussion symptoms experienced by American football players. Its diagnosis can only take place following the death of a person, through a neuropathological exam. The build-up of an abnormal form of tau protein in a specific pattern in the brain is the hallmark finding.

The researchers applied experimental flortaucipir PET scans to evaluate tau deposition in the brains of 26 living former NFL players between the ages of 40 and 69, who experienced cognitive, mood and behavior symptoms. They also assessed 31 men of the same ages without symptoms or histories of traumatic brain injuries.

Tau PET levels were found to be significantly higher among the players, compared to the control group, with the tau found in parts of the brain that have been confirmed in post-mortem cases to be areas impacted by neuropathologically diagnosed CTE.

The study authors also performed FDA-approved florbetapir PET scanning to assess amyloid plaque deposition, and found no difference between both groups, suggesting that symptoms experienced by athletes who have suffered repetitive head injuries in the past do not signal the onset of Alzheimer’s disease, another neurological condition characterized by the presence of tau and amyloid accumulation. Past diagnoses of CTE support this assessment, with the disease based, in part, on the pattern of tau deposition and a relative lack of Amyloid plaques.

"There is an interest in tau PET tracers with improved ability to detect the tau PET changes associated with not only AD, but with the tau pathology associated with certain other neurodegenerative diseases and with CTE," study co-author, Eric Reiman, executive director of Banner Alzheimer’s Institute, told HCB News.
  Pages: 1 - 2 >>

Molecular Imaging Homepage

You Must Be Logged In To Post A Comment

Erhöhen Sie Ihren Bekanntheitsgrad
Auktionen + Privatverkäufe
Den besten Preis erzielen
Geräte/Geräteteile kaufen
Den günstigsten Preis finden
Daily News
Die neuesten Nachrichten lesen
Alle DOTmed Benutzer durchsuchen
Ethik auf DOTmed
Unseren Ethik-Standard anzeigen
Gold-Parts Verkäufer-Programm
PH-Anfragen erhalten
Gold Service Dealer-Programm
Anfragen empfangen
Alle Gesundheitsdienstleister-Tools anzeigen
Einen Job suchen
Parts Hunter +EasyPay
Angebote für Geräteteile erhalten
Kürzlich zertifiziert
Kürzlich zertifizierte Benutzer anzeigen
Kürzlich bewertet
Kürzlich zertifizierte Benutzer anzeigen
Rental Central
Geräte billiger mieten
Geräte/Geräteteile verkaufen
Das meiste Geld erhalten
Service-Techniker Forum
Hilfe und Beratung finden
Einfache Angebots-Anfrage
Angebote für Geräte erhalten
Virtuelle Messe
Service für Geräte finden
Access and use of this site is subject to the terms and conditions of our LEGAL NOTICE & PRIVACY NOTICE
Property of and Proprietary to DOTmed.com, Inc. Copyright ©2001-2019 DOTmed.com, Inc.